The rabies vaccination is a core vaccination. Meaning, all cats, regardless of lifestyle should receive this vaccination. Rabies is a deadly virus that is transmitted between mammals. The rabies virus poses a large human health risk, which is why this vaccination is required by law. The vaccination age for pets can differ by state.T . Generally, a cat is initially vaccinated against rabies between 12-16 weeks of age. The frequency of vaccination is dependent on age, and vaccine history. Typically, after the initial vaccine is administered, a rabies booster is given 1 year later. Depending on the vaccine used, some rabies vaccinations in cats may be protective for 3 years. Your veterinarian will help determine if the 1- or 3-year rabies vaccination is best suited for your cat. If your cat has come in contact with or been bitten by an animal suspected of having rabies, your veterinarian should be contacted, and a rabies booster should be administered.